Concentrated Insulins : Practical Considerations for an Optimal Use
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Question 1: Amongst the following statements about glargine 300 units/ml, which one is false?
- Glargine at 300 units/ml is not bioequivalent to glargine 100 units/ml
- Transition of NPH insulin to glargine 300 units/ml will usually involve an immediate increase in the total daily dose of insulin
- After being opened, glargine 300 units/ml can be maintained at room temperature for a maximum of 42 days
- Glargine is available as a pre-filled pen only
Question 2: Amongst the following statements about lispro 200 units/ml, which one is false?
- Lispro 200 units/ml is indicated for patients who need to use more than 20 units of prandial insulin per day
- Lispro 200 units/ml has comparable pharmacokinetic characteristics to lispro 100 units/ml
- Lispro 200 units/ml can, like lispro 100 units/ml, be mixed with other insulins
- The primary advantage of lispro 200 units/ml is a reduction in the volume to inject
Question 3: Amongst the following statements about regular human insulin 500 units/ml, which one is false?
- This insulin would be indicated in a patient needing more than 150 units per day
- Its frequency of administration is 2 or 3 times per day
- When transitioning to this type of insulin, the recommended initial dose to be taken before breakfast will be higher than the dose taken before supper
- Even though this type of insulin has a basal effect, the doses have to be timed according to meals
Question 4: Which one of these insulins has the longest duration of action?
- Lispro 200 unit/ml
- Glargine 300 units/ml
- Degludec 200 units/ml
- Humaine regular 500 units/ml
Question 5: Among these statements, which one is true?
- Humain regular 500 IU/ml insulin is bioequivalent to the 100 IU/ml concentration.
- Degludec needs to be injected at the same time everyday in order to not change its efficacy.
- Human regular 500 IU/ml insulin is used in monotherapy as a prandial and basal insulin.
- Degludec is stored up to a maximum of 28 days after its first use.
Question 6: Which one of these statements concerning degludec is false?
- Degludec 200 IU/ml allows an injection with half the volume needed with degludec 100 IU/ml.
- A minimum delay of 16 hours is needed between 2 injections.
- Safety and efficacy have been established in children ≥ 1 years old.
- When transitioning from a basal insulin injected BID, it is recommended to decrease the dose by 20%.
Question 1 of 6
Among the following statements about glargine 300 units/ml, which one is false?
Question 2 of 6
Among the following statements about lispro 200 units/ml, which one is false?
Question 3 of 6
Among the following statements about regular human insulin 500 units/ml, which one is false?
Question 4 of 6
Which one of these insulins has the longest duration of action?
Question 5 of 6
Among these statements, which one is true?
Question 6 of 6
Which one of these statements concerning degludec is false?